黄薇园

个人信息

黄薇园，中国共产党党员，医学博士，教授、主任医师、博士生导师。现任海南省人民医院（海南医科大学附属海南医院）放射科负责人，医学影像技术专业负责人，医学影像诊断学教研室常务副主任。主要致力于中枢及头颈部重大疾病影像诊断及科研工作。

教育经历

2011/09-2014/06 复旦大学-复旦大学附属华山医院，影像医学与核医学，获博士学位

2007/09-2010/06 安徽医科大学-安徽医科大学第一附属医院，影像医学与核医学，获硕士学位

2002/09-2007/06 安徽医科大学，医学影像系，获学士学位

工作经历

2018/10-至今 海南省人民医院（海南医科大学附属海南医院），放射科，教授/主任医师

2024/11-2024/12 英国西英格兰大学，教师培训

2020/12-2021/06 中国科学院自动化研究所，分子影像国家重点实验室，访问学者

2019/05-2020/06 美国康奈尔医学院，MRI重点实验室，访问学者

2014/08-2018/09 海南省人民医院，放射科，主治医师/副主任医师

2010/07-2011/07 安徽医科大学第一附属医院，影像中心，医师

学术成果

持国家自然科学基金面上项目1项、青年项目1项、地区项目2项，主持海南省重点研发计划项目2项，以第一作者或通讯作者发表SCI论文30余篇。主要科研方向为中枢及头颈部重大疾病磁共振（MRI）多模功能序列研究，近年来主要致力于运用DCE、DWI、DSI、MRF等MRI多模功能序列预测鼻咽癌放疗抵抗，预测鼻咽癌近期远期预后及监测鼻咽癌乏氧状态。并运用HARDI、DSI、DCE及QSM观察鼻咽癌放疗后放射性脑微结构及认知功能损伤的纵向动态变化，以期实现早期诊断及预警。并尝试多学科合作探索MRI纳米载药系统及新型对比剂研发、乏氧增敏剂临床转化等。未来想要关注的方向为新型纳米MRI对比剂研发、鼻咽癌乏氧增敏治疗及靶向治疗疗效评估、人工智能辅助鼻咽癌智能诊疗体系构建研究等。

近三年发表论文（第一或通讯作者）

(1) Lin TC, Wang KJ, Li WZ, Wu G, Chen F, Huang WY. Interpretable multimodal MRI radiomics for predicting neoadjuvant chemotherapy response in nasopharyngeal carcinoma. BMC Med Imaging. 2025 Nov 25. doi: 10.1186/s12880-025-02071-8.

(2) Wenzhu Li, Jiali Song, Wu Gang, Mengying Dong, Yuting Liao, Zhijie Huang, Feng Chen*，Wei-yuan Huang*. Dynamic contrast-enhanced magnetic resonance imaging-based radiomics for predicting programmed death ligand 1 expression in nasopharyngeal carcinoma. BMC Med Imaging. 2025 Sep 26; 25(1): 377. doi: 10.1186/s12880-025-01917-5.

(3) Jie Sun^#, Xuewei Wu^#, Xiao Zhang^#, Weiyuan Huang^#, Xi Zhong^# , Xueyan Li^# , Kaiming Xue, Shuyi Liu, Xianjie Chen, Wenzhu Li, Xin Liu, Hui Shen, Jingjing You, Wenle He, Zhe Jin, Lijuan Yu, Yuange Li* , Shuixing Zhang* , and Bin Zhang*. Radiomic Model Associated with Tumor Microenvironment Predicts Immunotherapy Response and Prognosis in Patients with Locoregionally Advanced Nasopharyngeal Carcinoma. Research. 2 Jun 2025. DOI: 10.34133/research.0749

(4) Luo Li, Xin Qin, Qinlei Cai, Yuting Liao, Shishi Luo, Shanxi Guo, Feng Chen, Weiyuan Huang*. Bilateral adrenal heterogeneity in contrast-enhanced CT for differentiating nodule-negative primary aldosteronism. Abdominal Radiology. 2025 Jun 4. doi: 10.1007/s00261-025-05025-4.

(5) Jin X, Li WZ, Guo YH, Wu G, Huang WY*, Chen F*. Predicting progression-free survival using dynamic contrast-enhanced imaging-based radiomics in advanced nasopharyngeal carcinoma patients treated with nimotuzumab. European Radiology. 2025 Feb 14. doi: 10.1007/s00330-025-11433-3.

(6) Guo Li, Qinlei Cai, Xin Qin, Shishi Luo, Shanxi Guo, Yihao Guo, Feng Chen*, Weiyuan Huang*. Hepatic artery diameter predicts bleeding risk after gastroesophageal varices treatment: a contrastenhanced CT study. Abdominal Radiology. 2024 Oct; 49(10): 3364-3373. doi: 10.1007/s00261-024-04291-y.

(7) Tiansheng Li, Yihao Guo, Xin Jin, Tao Liu, Gang Wu, Weiyuan Huang*, Feng Chen*. Dynamic monitoring of radiation-induced white matter microstructure injury in nasopharyngeal carcinoma via high-angular resolution diffusion imaging. Brain Research. 2024,1833:148851.https://doi.org/10.1016/j.brainres.2024.148851

(8) Qianyu Yang^#, Gang Wu^#, Yefeng Yang^#, Yang Zhou, Jiali Song, Huile Gao*, Weiyuan Huang*. GSH-Responsive Shape-Transformable Nanotheranostics for Dual-Modal T1/T2 MRI-Guided Enhanced PDT of Nasopharyngeal Carcinoma. Advanced Functional Materials, 2402194. https://doi.org/10.1002/adfm.202402194.

(9) Hailin Li^#, Weiyuan Huang^#, Siwen Wang, Priya S. Balasubramanian, Gang Wu, Mengjie Fang, Xuebin Xie, Jie Zhang, Di Dong*, Jie Tian*, and Feng Chen*. Comprehensive integrated analysis of MR and DCE-MR radiomics models for prognostic prediction in nasopharyngeal carcinoma. Visual Computing for Industry, Biomedicine, and Art. 2023, 6 (23). https://doi.org/10.1186/s42492-023-00149-0.

(10) Kun Wang^#, Weiyuan Huang^#, Xianshan Chen^#, Gao Li, Na Li, Xiuming Huang, Xuqiang Liao, Jiali Song, Qianyu Yang, Kun He, An Yu, Xin Feng, Zeyu Zhang, Chongwei Chi, Jie Tian^*, Fengxia Chen^*, Feng Chen^*. Efficacy of Near-Infrared Fluorescence Video-Assisted Thoracoscopic Surgery for Small Pulmonary Nodule Resection with Indocyanine Green Inhalation: A Randomized Clinical Trial. Annals of Surgical Oncology. 2023 Sep;30(9):5912-5922. doi: 10.1245/s10434-023-13753-4.

(11) Qianyu Yang, Yingkun Guo, Yang Zhou, Jiali Song, Yujun Song, Hanmei Li, Huile Gao^*, Weiyuan Huang^*. Multifunctional Nanotheranostics for Dual-Modal Imaging-Guided Precision Therapy of Nasopharyngeal Carcinoma. Molecular Pharmaceutics. 2023 Sep 4;20(9):4743-4757. doi: 10.1021/acs.molpharmaceut.3c00491.

(12) Yihao Guo, Ganmian Dai, Xiaoli Xiong, Xiaoyi Wang, Huijuan Chen, Xiaoyue Zhou, Weiyuan Huang^*, Feng Chen^*. Intravoxel incoherent motion radiomics nomogram for predicting tumor treatment responses in nasopharyngeal carcinoma. Translational Oncology. 2023 May;31:101648. doi: 10.1016/j.tranon.2023.101648.

(13) Qihao Zhang^#, Gang Wu^#, Qianyu Yang, Tiansheng Li, Pianpian Chen, Jiao Li, Wei-yuan Huang^*. Survival Rate Prediction of Nasopharyngeal Carcinoma Patients based on MRI and Gene Expression using Deep Neural Network. Cancer science. 2023 Apr;114(4):1596-1605. doi: 10.1111/cas.15704. Epub 2023 Jan 9.

(14) Weiyuan Huang^#, Tao Liu^#, Huijuan Chen, Qingqing Fu, Lili Fu, Xiaolin Xu, Liting Liu, Yihao Guo, Priya S Balasubramanian, Feng Chen^*. Mapping white matter structural and network alterations in betel quid-dependent. Frontier in Psychiatry. 2022 Dec 05. doi.org/10.3389/fpsyt.2022.1036728.

(15) Wenzhu Li^#, Gang Wu^#, Tiansheng Li, Ganmian Dai, Yuting Liao, Qianyu Yang, Feng Chen^*, Weiyuan Huang^*. Dynamic contrast-enhanced magnetic resonance imaging-based radiomics for the prediction of progression-free survival in advanced nasopharyngeal carcinoma. Frontiers in Oncology. 2022 Oct 13; 12:955866. doi: 10.3389/fonc.2022.955866.

(16) Wenhui Huang^#, Kun Wang^#, Weiyuan Huang^#, Zicong He, Jingming Zhang, Bin Zhang, Zhiyuan Xiong, Kelly McCabe Gillen, Wenzhe Li, Feng Chen, Xing Yang^*, Shuixing Zhang^*, Jie Tian^*. Carbonic anhydrase IX stratifies patient prognosis and identifies nodal status in animal models of nasopharyngeal carcinoma using a targeted imaging strategy. European Journal of Nuclear Medicine and Molecular Imaging. 2022, Nov; 49(13): 4427-4439. doi: 10.1007/s00259-022-05922-6.

(17) Lili Fu^#, Huijuan Chen^#, Tao Liu, Liting Liu, Qingqing Fu, Weiyuan Huang^*, Feng Chen^*. Altered spontaneous brain activity in betel quid dependence chewers: a resting-state functional MRI study with percent amplitude of fluctuation. Frontier in Psychiatry. 2022 May 2;13:830541. doi: 10.3389/fpsyt. 2022.830541.

(18) Weiyuan Huang, Elizabeth M. Sweeney, Ulrike W. Kaunzner, Yi Wang, Susan A. Gauthier, Thanh D. Nguyen^*. Quantitative susceptibility mapping versus phase imaging to identify multiple sclerosis iron rim lesions with demyelination. Journal of neuroimaging. 2022 Jul;32(4):667-675. doi: 10.1111/jon.12987.

(19) Weiyuan Huang^#, Kun Wang^#, Fengxia Chen, Gao Li, Xianshan Chen, Qianyu Yang , Na Li, Kunshan He, Feng Chen, Jie Tian^*. Intraoperative Fluorescence Visualization in Thoracoscopic Surgery. Annals of Thoracic Surgery. 2022 Mar 29: S0003-4975 (22) 00467-2. doi: 10.1016/j.athoracsur.2022.03.040.

学术组织兼职

中华医学会放射学分会青年委员会委员；中华医学会放射学分会分子影像学组委员；中国医师协会放射学分会AI学组委员；中国医师协会放射学分会组织与会员学组委员；中国医学装备协会磁共振成像装备与技术专委会AI学组委员；海南省医学会放射学分会青年委员会副主任委员；海南省医师协会放射学分会副主任委员。

荣誉

海南省高层次人才（D类）；

海南省第三届优秀研究生导师；

海南省自然科学奖二等奖（第一完成人）；

海南省医学科学技术奖二等奖（第一完成人）；

2025年度海南医科大学十佳教师；

2022年度海南省人民医院“科研先进工作者”，2023年度海南省人民医院“十佳医生”，2023年度海南省人民医院“科研先进工作者”，2023年度优秀党员，2024年度海南省人民医院“十佳教师”等。

联系方式

weiyuanhuang@muhn.edu.cn